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An Au(i)-catalyzed rearrangement/cyclization cascade toward the synthesis of 2-substituted-1,4,5,6-tetrahydrocyclopenta[b]pyrrole

  • Xue Qing Mou
  • , Zheng Liang Xu
  • , Shao Hua Wang*
  • , Dao Yong Zhu
  • , Jie Wang
  • , Wen Bao
  • , Shi Jiang Zhou
  • , Chao Yang
  • , Di Zhang
  • *Corresponding author for this work
  • Lanzhou University
  • Key Laboratory of Drug Targeting and Drug Delivery System

Research output: Contribution to journalArticlepeer-review

Abstract

An Au(i)-catalyzed tandem reaction for the synthesis of 2-phenyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole derivatives from 1-(1-hydroxy-3-phenylprop-2-yn-1-yl)cyclobutanol and primary amines or NH4OAc has been developed to afford a series of polysubstituted pyrroles in moderate to good yields.

Original languageEnglish
Pages (from-to)12064-12067
Number of pages4
JournalChemical Communications
Volume51
Issue number60
DOIs
StatePublished - 4 Aug 2015
Externally publishedYes

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