Airy-beam tomographic microscopy

Jian Wang; Xuanwen Hua; Changliang Guo; Wenhao Liu; Shu Jia

doi:10.1364/OPTICA.389894

Airy-beam tomographic microscopy

Jian Wang
, Xuanwen Hua
, Changliang Guo
, Wenhao Liu
, Shu Jia^*

^*Corresponding author for this work

School of Physics, Harbin Institute of Technology
Georgia Institute of Technology

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

We introduce Airy-beam tomographic microscopy (ATM) for high-resolution, volumetric, inertia-free imaging of biological specimens. The work exploits the highly adjustable Airy trajectories in the 3D space, transforming the conventional telecentric wide-field imaging scheme that requires sample or focal-plane scanning to acquire 3D information. The results present a consistent near-diffraction-limited 3D resolution across a tenfold extended imaging depth compared to widefield microscopy. We anticipate the strategy to not only offer a promising paradigm for 3D optical microscopy, but also be translated to other non-optical waveforms.

Original language	English
Pages (from-to)	790-794
Number of pages	5
Journal	Optica
Volume	7
Issue number	7
DOIs	https://doi.org/10.1364/OPTICA.389894
State	Published - 20 Jul 2020
Externally published	Yes

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10.1364/OPTICA.389894

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title = "Airy-beam tomographic microscopy",

abstract = "We introduce Airy-beam tomographic microscopy (ATM) for high-resolution, volumetric, inertia-free imaging of biological specimens. The work exploits the highly adjustable Airy trajectories in the 3D space, transforming the conventional telecentric wide-field imaging scheme that requires sample or focal-plane scanning to acquire 3D information. The results present a consistent near-diffraction-limited 3D resolution across a tenfold extended imaging depth compared to widefield microscopy. We anticipate the strategy to not only offer a promising paradigm for 3D optical microscopy, but also be translated to other non-optical waveforms.",

author = "Jian Wang and Xuanwen Hua and Changliang Guo and Wenhao Liu and Shu Jia",

note = "Publisher Copyright: {\textcopyright} 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.",

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AU - Wang, Jian

AU - Hua, Xuanwen

AU - Guo, Changliang

AU - Liu, Wenhao

AU - Jia, Shu

PY - 2020/7/20

Y1 - 2020/7/20

N2 - We introduce Airy-beam tomographic microscopy (ATM) for high-resolution, volumetric, inertia-free imaging of biological specimens. The work exploits the highly adjustable Airy trajectories in the 3D space, transforming the conventional telecentric wide-field imaging scheme that requires sample or focal-plane scanning to acquire 3D information. The results present a consistent near-diffraction-limited 3D resolution across a tenfold extended imaging depth compared to widefield microscopy. We anticipate the strategy to not only offer a promising paradigm for 3D optical microscopy, but also be translated to other non-optical waveforms.

AB - We introduce Airy-beam tomographic microscopy (ATM) for high-resolution, volumetric, inertia-free imaging of biological specimens. The work exploits the highly adjustable Airy trajectories in the 3D space, transforming the conventional telecentric wide-field imaging scheme that requires sample or focal-plane scanning to acquire 3D information. The results present a consistent near-diffraction-limited 3D resolution across a tenfold extended imaging depth compared to widefield microscopy. We anticipate the strategy to not only offer a promising paradigm for 3D optical microscopy, but also be translated to other non-optical waveforms.

UR - https://www.scopus.com/pages/publications/85090907138

U2 - 10.1364/OPTICA.389894

DO - 10.1364/OPTICA.389894

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JO - Optica

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Airy-beam tomographic microscopy

Abstract

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