Active nanomotors surpass passive nanomedicines: current progress and challenges

Shuqin Chen; Yuduo Chen; Mingming Fu; Qinghua Cao; Bo Wang; Wenjun Chen; Xing Ma

doi:10.1039/d2tb00556e

Active nanomotors surpass passive nanomedicines: current progress and challenges

Shuqin Chen
, Yuduo Chen
, Mingming Fu
, Qinghua Cao
, Bo Wang
, Wenjun Chen^*
, Xing Ma^*

^*Corresponding author for this work

Harbin Institute of Technology (Shenzhen)
Shanghai University of Engineering Science
Shenzhen Bay Laboratory

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

Artificial nanomotors show advantages over traditional nanomedicines in biomedical applications due to their active locomotion by converting various energy sources into mechanical force in situ. Currently, nanomotors are attracting wide attention in diagnosis and therapy towards clinical applications. In this perspective, we summarize recent developments of nanomotors in biomedical applications, including targeted drug delivery, biological barrier penetration, and diagnostics and cancer treatment. The development of nanomotors in biomedicine still faces considerable challenges and practical difficulties towards clinical use, which are discussed in detail. Finally, we propose potential solutions that may help the development of nanomotors towards advanced diagnostics and therapy.

Original language	English
Pages (from-to)	7099-7107
Number of pages	9
Journal	Journal of Materials Chemistry B
Volume	10
Issue number	37
DOIs	https://doi.org/10.1039/d2tb00556e
State	Published - 13 Apr 2022
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1039/d2tb00556e

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title = "Active nanomotors surpass passive nanomedicines: current progress and challenges",

abstract = "Artificial nanomotors show advantages over traditional nanomedicines in biomedical applications due to their active locomotion by converting various energy sources into mechanical force in situ. Currently, nanomotors are attracting wide attention in diagnosis and therapy towards clinical applications. In this perspective, we summarize recent developments of nanomotors in biomedical applications, including targeted drug delivery, biological barrier penetration, and diagnostics and cancer treatment. The development of nanomotors in biomedicine still faces considerable challenges and practical difficulties towards clinical use, which are discussed in detail. Finally, we propose potential solutions that may help the development of nanomotors towards advanced diagnostics and therapy.",

author = "Shuqin Chen and Yuduo Chen and Mingming Fu and Qinghua Cao and Bo Wang and Wenjun Chen and Xing Ma",

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T1 - Active nanomotors surpass passive nanomedicines

T2 - current progress and challenges

AU - Chen, Shuqin

AU - Chen, Yuduo

AU - Fu, Mingming

AU - Cao, Qinghua

AU - Wang, Bo

AU - Chen, Wenjun

AU - Ma, Xing

PY - 2022/4/13

Y1 - 2022/4/13

N2 - Artificial nanomotors show advantages over traditional nanomedicines in biomedical applications due to their active locomotion by converting various energy sources into mechanical force in situ. Currently, nanomotors are attracting wide attention in diagnosis and therapy towards clinical applications. In this perspective, we summarize recent developments of nanomotors in biomedical applications, including targeted drug delivery, biological barrier penetration, and diagnostics and cancer treatment. The development of nanomotors in biomedicine still faces considerable challenges and practical difficulties towards clinical use, which are discussed in detail. Finally, we propose potential solutions that may help the development of nanomotors towards advanced diagnostics and therapy.

AB - Artificial nanomotors show advantages over traditional nanomedicines in biomedical applications due to their active locomotion by converting various energy sources into mechanical force in situ. Currently, nanomotors are attracting wide attention in diagnosis and therapy towards clinical applications. In this perspective, we summarize recent developments of nanomotors in biomedical applications, including targeted drug delivery, biological barrier penetration, and diagnostics and cancer treatment. The development of nanomotors in biomedicine still faces considerable challenges and practical difficulties towards clinical use, which are discussed in detail. Finally, we propose potential solutions that may help the development of nanomotors towards advanced diagnostics and therapy.

UR - https://www.scopus.com/pages/publications/85139375994

U2 - 10.1039/d2tb00556e

DO - 10.1039/d2tb00556e

M3 - 文献综述

C2 - 35543361

AN - SCOPUS:85139375994

SN - 2050-750X

VL - 10

SP - 7099

EP - 7107

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 37

ER -

Active nanomotors surpass passive nanomedicines: current progress and challenges

Abstract

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