A structural snapshot of the rhodopsin-arrestin complex

Yanyong Kang; Xiang Gao; X. Edward Zhou; Yuanzheng He; Karsten Melcher; H. Eric Xu

doi:10.1111/febs.13561

A structural snapshot of the rhodopsin-arrestin complex

Yanyong Kang
, Xiang Gao
, X. Edward Zhou
, Yuanzheng He
, Karsten Melcher
, H. Eric Xu^*

^*Corresponding author for this work

Van Andel Institute
CAS - Shanghai Institute of Materia Medica

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The crystal structure of the rhodopsin-arrestin complex provides important insights into how G protein-coupled receptor signaling is terminated by arrestin and a structural basis for understanding the mechanism of arrestin-based signaling.

Original language	English
Pages (from-to)	816-821
Number of pages	6
Journal	FEBS Journal
Volume	283
Issue number	5
DOIs	https://doi.org/10.1111/febs.13561
State	Published - Mar 2016
Externally published	Yes

Keywords

G protein
G protein-coupled receptors
Rhodopsin
arrestin
biased signalling

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10.1111/febs.13561

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@article{656f43b79f8e4e3794e7306ba2a4ae1b,

title = "A structural snapshot of the rhodopsin-arrestin complex",

abstract = "The crystal structure of the rhodopsin-arrestin complex provides important insights into how G protein-coupled receptor signaling is terminated by arrestin and a structural basis for understanding the mechanism of arrestin-based signaling.",

keywords = "G protein, G protein-coupled receptors, Rhodopsin, arrestin, biased signalling",

author = "Yanyong Kang and Xiang Gao and Zhou, \{X. Edward\} and Yuanzheng He and Karsten Melcher and Xu, \{H. Eric\}",

note = "Publisher Copyright: {\textcopyright} 2015 FEBS.",

year = "2016",

month = mar,

doi = "10.1111/febs.13561",

language = "英语",

volume = "283",

pages = "816--821",

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TY - JOUR

T1 - A structural snapshot of the rhodopsin-arrestin complex

AU - Kang, Yanyong

AU - Gao, Xiang

AU - Zhou, X. Edward

AU - He, Yuanzheng

AU - Melcher, Karsten

AU - Xu, H. Eric

PY - 2016/3

Y1 - 2016/3

N2 - The crystal structure of the rhodopsin-arrestin complex provides important insights into how G protein-coupled receptor signaling is terminated by arrestin and a structural basis for understanding the mechanism of arrestin-based signaling.

AB - The crystal structure of the rhodopsin-arrestin complex provides important insights into how G protein-coupled receptor signaling is terminated by arrestin and a structural basis for understanding the mechanism of arrestin-based signaling.

KW - G protein

KW - G protein-coupled receptors

KW - Rhodopsin

KW - arrestin

KW - biased signalling

UR - https://www.scopus.com/pages/publications/84960078752

U2 - 10.1111/febs.13561

DO - 10.1111/febs.13561

M3 - 文章

C2 - 26467309

AN - SCOPUS:84960078752

SN - 1742-464X

VL - 283

SP - 816

EP - 821

JO - FEBS Journal

JF - FEBS Journal

IS - 5

ER -

A structural snapshot of the rhodopsin-arrestin complex

Abstract

Keywords

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