A review oriented by structure-activity relationship: Preparation, bioactivities, and applications of Laminaria japonica polysaccharides

Xin Yue Li; Zi Xuan Wang; Long Zhu Li; Li Huang; Yan Chao Wu; Hui Jing Li

doi:10.1016/j.ijbiomac.2025.147675

A review oriented by structure-activity relationship: Preparation, bioactivities, and applications of Laminaria japonica polysaccharides

Xin Yue Li
, Zi Xuan Wang
, Long Zhu Li
, Li Huang
, Yan Chao Wu^*
, Hui Jing Li

^*Corresponding author for this work

Harbin Institute of Technology Weihai

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Laminaria japonica is a macroalga with traditional medicinal and edible significance. This study focuses on the conformational relationship of Laminaria japonica polysaccharides (LJPs), specifically examining how the preparation process influences their structural characteristics. Furthermore, it elucidates the inherent connection between molecular structure and biological function. This review provides new insights into the structure-activity relationships of LJPs, establishing a scientific foundation for their function-oriented production and application.

Original language	English
Article number	147675
Journal	International Journal of Biological Macromolecules
Volume	328
DOIs	https://doi.org/10.1016/j.ijbiomac.2025.147675
State	Published - Nov 2025
Externally published	Yes

Keywords

Alginate
Application
Fucoidan
Laminaria japonica
Laminarin
Structure-activity relationship

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10.1016/j.ijbiomac.2025.147675

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@article{cd053a40bf0048cc8fd877bd5faacd3d,

title = "A review oriented by structure-activity relationship: Preparation, bioactivities, and applications of Laminaria japonica polysaccharides",

abstract = "Laminaria japonica is a macroalga with traditional medicinal and edible significance. This study focuses on the conformational relationship of Laminaria japonica polysaccharides (LJPs), specifically examining how the preparation process influences their structural characteristics. Furthermore, it elucidates the inherent connection between molecular structure and biological function. This review provides new insights into the structure-activity relationships of LJPs, establishing a scientific foundation for their function-oriented production and application.",

keywords = "Alginate, Application, Fucoidan, Laminaria japonica, Laminarin, Structure-activity relationship",

author = "Li, \{Xin Yue\} and Wang, \{Zi Xuan\} and Li, \{Long Zhu\} and Li Huang and Wu, \{Yan Chao\} and Li, \{Hui Jing\}",

note = "Publisher Copyright: {\textcopyright} 2025 Elsevier B.V.",

year = "2025",

month = nov,

doi = "10.1016/j.ijbiomac.2025.147675",

language = "英语",

volume = "328",

journal = "International Journal of Biological Macromolecules",

issn = "0141-8130",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - A review oriented by structure-activity relationship

T2 - Preparation, bioactivities, and applications of Laminaria japonica polysaccharides

AU - Li, Xin Yue

AU - Wang, Zi Xuan

AU - Li, Long Zhu

AU - Huang, Li

AU - Wu, Yan Chao

AU - Li, Hui Jing

PY - 2025/11

Y1 - 2025/11

N2 - Laminaria japonica is a macroalga with traditional medicinal and edible significance. This study focuses on the conformational relationship of Laminaria japonica polysaccharides (LJPs), specifically examining how the preparation process influences their structural characteristics. Furthermore, it elucidates the inherent connection between molecular structure and biological function. This review provides new insights into the structure-activity relationships of LJPs, establishing a scientific foundation for their function-oriented production and application.

AB - Laminaria japonica is a macroalga with traditional medicinal and edible significance. This study focuses on the conformational relationship of Laminaria japonica polysaccharides (LJPs), specifically examining how the preparation process influences their structural characteristics. Furthermore, it elucidates the inherent connection between molecular structure and biological function. This review provides new insights into the structure-activity relationships of LJPs, establishing a scientific foundation for their function-oriented production and application.

KW - Alginate

KW - Application

KW - Fucoidan

KW - Laminaria japonica

KW - Laminarin

KW - Structure-activity relationship

UR - https://www.scopus.com/pages/publications/105016096775

U2 - 10.1016/j.ijbiomac.2025.147675

DO - 10.1016/j.ijbiomac.2025.147675

M3 - 文献综述

AN - SCOPUS:105016096775

SN - 0141-8130

VL - 328

JO - International Journal of Biological Macromolecules

JF - International Journal of Biological Macromolecules

M1 - 147675

ER -

A review oriented by structure-activity relationship: Preparation, bioactivities, and applications of Laminaria japonica polysaccharides

Abstract

Keywords

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