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A microplatform for measurement of cell mechanical properties

  • Hao Tang
  • , Zheyao Wang
  • , Shouhong Jin
  • , Qiong Wu
  • Tsinghua University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

a novel microplatform has been fabricated on SOI wafers for applying uniaxial strain to a single cell while simultaneously measuring its force response. This microplatform includes two chevron thermal actuators able to bring cells 14 um stretching displacement and an easy-fabricating piezoresistivelateral force sensor with a sensitivity of 56.166 (V/V)/N, which makes it an effective tool for analyzing the mechanics of a single cell. This lateral force sensor has a low requirement for the lithography alignment and its piezoresistors are formed by one-step surface ion implantation. A front-side releasing method is applied to suspend this microplatform. This method helps us avoid from the friction problems and low yield rates that common appeared in the traditional method. Our design provides a good reference for devising lateral force sensors and suspending complex microstructures.

Original languageEnglish
Title of host publicationIEEE SENSORS 2014, Proceedings
EditorsFrancisco J. Arregui
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1619-1622
Number of pages4
EditionDecember
ISBN (Electronic)9781479901616
DOIs
StatePublished - 12 Dec 2014
Externally publishedYes
Event13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain
Duration: 2 Nov 20145 Nov 2014

Publication series

NameProceedings of IEEE Sensors
NumberDecember
Volume2014-December
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229

Conference

Conference13th IEEE SENSORS Conference, SENSORS 2014
Country/TerritorySpain
CityValencia
Period2/11/145/11/14

Keywords

  • Cell mechanics
  • Lateral force sensor
  • Piezoresistive
  • Single cell
  • Thermal actuator
  • Uniaxial stretch

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