A fully automatic breast ultrasound image segmentation approach based on neutro-connectedness

Breast tumor segmentation is an important step of breast ultrasound (BUS) computer-aided diagnosis (CAD) systems. However, because of the poor quality of BUS images, it's a challenging task to develop a robust and accurate segmentation algorithm. Much progress has been made on applying fuzzy connectedness to segment objects from low quality images. However, the fuzzy connectedness method still has difficulty in segmenting objects with weak boundaries. The neutrosophic set theory has been widely applied to image processing, and shows more strengths in modeling uncertainty and indeterminacy. In this paper, two new concepts of neutrosophic subset and neutrosophic connectedness (neutro-connectedness) were defined to generalize the fuzzy subset and fuzzy connectedness. The newly proposed neutro-connectedness models the inherent uncertainty and indeterminacy of the spatial topological properties of the image. The proposed method is applied to a breast ultrasound database with 131 cases, and its performance is evaluated by similarity ratio (SIR), false positive ratio (FPR) and average Hausdroff error (AHE). In comparison with the fuzzy connectedness segmentation method, the proposed method is more accurate and robust in segmenting tumors in BUS images.