A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

Binbin Huang; Lin Guo; Wujiong Xia

doi:10.1039/d1gc00317h

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

Binbin Huang
, Lin Guo^*
, Wujiong Xia

^*Corresponding author for this work

Harbin Institute of Technology

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et₃N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

Original language	English
Pages (from-to)	2095-2103
Number of pages	9
Journal	Green Chemistry
Volume	23
Issue number	5
DOIs	https://doi.org/10.1039/d1gc00317h
State	Published - 7 Mar 2021
Externally published	Yes

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abstract = "A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.",

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N2 - A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

AB - A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

UR - https://www.scopus.com/pages/publications/85102961665

U2 - 10.1039/d1gc00317h

DO - 10.1039/d1gc00317h

M3 - 文章

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VL - 23

SP - 2095

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JO - Green Chemistry

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ER -

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

Abstract

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