形状记忆聚合物微纳米纤维膜在生物医学中的应用进展

As a class of smart materials, shape memory polymers (SMPs) can remember the temporary shape and return to the original shape under the condition of the external stimuli. The shape memory micro/nanofibers prepared by electrospinning technology possess a three-dimensional structure which is similar to the natural extracellular matrix. Therefore, it shows great application prospect in the biomedical field, especially in tissue engineering. Moreover, shape memory micro/nanofiber membranes bring more and more opportunities for the rapid development of personalized and smart biomedical devices. This paper reviews of SMP micro/nanofiber membranes, including preparation, structure, morphology and driving methods. We also summarize the applications of SMP micro/ nanofiber membranes in the brackets of bone tissue, bone tissue repair, nerve scaffolds and cell culture research. Furthermore, analysis other structures used in the biomedical field are discussed. Finally, we conclude the challenges and the perspectives of SMPs in the future.