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傅 里 叶 光 场 显 微 镜 的 进 展 及 其 生 物 应 用(特 邀)

Translated title of the contribution: Advance in Fourier Light-Field Microscopy and Its Biological Application (Invited)
  • Qianbo Liu
  • , Deer Su
  • , Youming Xiao
  • , Zonglin Guo
  • , Jin Wu
  • , Jian Wang
  • , Changliang Guo*
  • , Haoyu Li*
  • , Wenhao Liu*
  • *Corresponding author for this work
  • Harbin Institute of Technology
  • School of Physics, Harbin Institute of Technology
  • Peking University

Research output: Contribution to journalReview articlepeer-review

Abstract

Light-field microscopy has demonstrated remarkable potential in biomedical imaging. However, its inherent challenges—such as uneven spatial sampling and reconstruction artifacts—have limited its broader application. To address these issues, this paper introduces the recent advancements in Fourier light-field microscopy (FLFM). By recording light field information in the Fourier domain, FLFM achieves a consistent aliasing of both spatial and angular components of incident light. This innovative approach effectively mitigates reconstruction artifacts and enhances the uniformity of imaging resolution. In this work, we provide a comprehensive explanation of the imaging principles, system designs, and reconstruction algorithms of FLFM, comparing its point spread function to that of conventional light-field microscopy. Furthermore, we explore the application of FLFM in biological research, particularly in subcellular imaging and model organism studies. Finally, we offer insights into the future directions of FLFM.

Translated title of the contributionAdvance in Fourier Light-Field Microscopy and Its Biological Application (Invited)
Original languageChinese (Traditional)
Article number1817004
JournalLaser and Optoelectronics Progress
Volume62
Issue number18
DOIs
StatePublished - Sep 2025
Externally publishedYes

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